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Description

In some instances, conventionally used methods of sterilization (e.g., heat treatment (e.g., in an autoclave), gamma irradiation, filtration) lead to irreversible degradation of the therapeutic agent in the formulation or composition

This extended half-life is also why results take time to appear

[DOI] [PubMed] [Google Scholar] 106.Balenovic D., Barisic I., Prkacin I., Horvat I., Udovicic M., Uzun S., Strinic D., Pevec D., Drmic D., Radic B., et al